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The Eph family of receptor tyrosine kinases and their ephrin ligands play a crucial role in various cellular processes, including cell migration, adhesion, and differentiation. The Eph/ephrin system is involved in the development and maintenance of tissue architecture, and its dysregulation has been implicated in various diseases, including cancer and neurological disorders. This review aims to summarize the current understanding of Eph/ephrin biochemistry, highlighting the structural and functional aspects of these molecules. (You can add your favorite references here) To